American Cruise Lines
American Cruise Lines, the leader in U.S. river and coastal cruising, offers modern small ships and over 50 itineraries across 35 states. Enjoy spacious staterooms, personalized service, regional cuisine, and enriching excursions as you explore America’s iconic waterways.
Sail with American Cruise Lines
American Cruise Lines is proudly the only American-owned and operated cruise line. All ships are built in the USA, flagged in the USA, and crewed by Americans.
Their intimate ships offer a unique blend of luxury and heritage, inviting you to experience the warmth of personalized service as you explore the hidden gems of the United States.
Come aboard and cruise the Mississippi River, New England, Alaska, Pacific Northwest and the Southeast.
Current Promotions
Featured Departures
Lower Mississippi River Cruise
Memphis, Tennessee to New Orleans, Louisiana (or reverse)
8 Nights | Jan – Dec 2026
Aboard American Serenade, American Symphony, American Melody, American Splendor, or American Heritage
Sail the Lower Mississippi on an intimate Modern Riverboat. Enjoy Southern history, grand estates, local culture, guided excursions, and nightly onboard entertainment.
Member price from $4,915*
Advertised rate is based on the 11/10/26 departure.
Southeast Sea Islands Cruise
Charleston, South Carolina to Amelia Island, Florida (or reverse)
8 Nights | Jan – Dec 2026
Aboard American Legend, American Eagle, American Liberty, American Glory, or
American Independence
Cruise the Southeast coast from Charleston to Amelia Island. Explore historic towns, islands, and ports while enjoying regional cuisine, private balconies, and personalized service.
Member price from $5,630*
Advertised rate is based on the 11/17/26 departure.
Celebrate America's 250th on an Extended Voyage
American Cruise Lines invites you to embark on an extraordinary adventure with their most expansive itineraries, designed for those seeking a deeper exploration of America’s most treasured destinations. In celebration of the 250th anniversary of the signing of the Declaration of Independence, many of these 2026 cruises highlight the regions and landmarks central to our nation’s founding—including a brand-new Revolutionary War Cruise.
Travel through 15 U.S. states, sailing coast to coast on three U.S. rivers. From the banks of the Tennessee and Mississippi Rivers to the hallowed grounds of the East Coast, explore key moments in American history. Enjoy a spring journey from Key West to Alaska, or take in fall colors from the Last Frontier to the Chesapeake Bay.
American Cruise Lines makes your travel experience seamless, including access to a dedicated Cruise Concierge to assist you throughout your journey. Your Cruise Concierge will help reserve your excursions and handle all travel and accommodations between cruise segments.
Choose from:
- Civil War Battlefields Cruise | The Capture of New Orleans to The Battle of Gettysburg | 36 Days / 35 Nights
- The Great United States Cruise | Portland, OR to Boston, MA | 52 Days / 51 Nights
- Spring Across America | Charleston, SC to Juneau, AK | 51 Days / 50 Nights
- Great American Fall Foliage Cruise | Juneau, AK to Washington, D.C. | 55 Days / 54 Nights
- Revolutionary War Cruise | Albany, NY to Washington, D.C. | 32 Days / 31 Nights
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