American Cruise Lines
With 50 itineraries across 35 states, American Cruise Lines is your leader in U.S. river and coastal cruising. Enjoy spacious staterooms, personalized service, regional cuisine, and enriching excursions as you explore America’s iconic waterways.
Sail with American Cruise Lines
American Cruise Lines is proudly the only American-owned and operated cruise line. All ships are built in the USA, flagged in the USA, and crewed by Americans.
Their intimate ships offer a unique blend of luxury and heritage, inviting you to experience the warmth of personalized service as you explore the hidden gems of the United States.
Come aboard and cruise the Mississippi River, New England, Alaska, Pacific Northwest and the Southeast.
Current Promotions
Featured Departure
Spanish moss drapes over Savannah’s storied squares while Charleston’s cobblestone streets meander between grand homes and garden gates. Along the Intracoastal Waterway, dolphins surface near quiet marshes before Jekyll and Amelia Islands reveal histories shaped by Gilded Age elegance, maritime charm, and Southern hospitality. American Cruise Lines brings these close-to-home discoveries into focus aboard small ships designed for smooth sailing, personalized service, and a more intimate way to explore America.
American Cruise Line Voyages Include: Most ships built after 2023 with no more than 100 guests, private balconies, guided excursions at each port, all onboard meals and signature evening cocktail hour, and more.
Southeast Sea Islands
Charleston, South Carolina to Amelia Island, Florida
9 Days | Jan – Dec 2027
Hilton Head Island • Savannah • Jekyll Island • St. Simons Island
Member price from $6,995*
Advertised rate is based on 11/15/27 departure in a Premium Balcony Stateroom.
Specialty Themed Cruises on America's Rivers & Coasts
American Cruise Lines offers a wide variety of theme cruises celebrating music, history, art, literature, cuisine, and the natural beauty of the regions they visit.
Every itinerary is built around the unique character of the region it explores. Whether following in the footsteps of Lewis and Clark, discovering the world of Mark Twain along the Mississippi River, admiring spectacular fall foliage, exploring local art and culinary traditions, visiting celebrated vineyards, or searching for whales along the coast, these experiences are woven naturally into your voyage. Select itineraries also feature seasonal celebrations, including Tulip Season, Thanksgiving, Christmas, and New Year's cruises.
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